Table 1.
List of the main hemodynamic parameters of animals in the control and Hepa Wash groups
|
Time [h] |
T0 |
T4 |
T8 |
T12 |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Group | Controls (n=5) | Hepa Wash (n=6) | MARS (n=2) | Control (n=5) | Hepa Wash (n=6) | MARS (n=2) | Control (n=5) | Hepa Wash (n=6) | MARS (n=2) | Control (n=2) | Hepa Wash (n=6) | MARS (n=1) |
| Cerebral perfusion pressure [mmHg] |
87 ± 10 |
90 ± 4 |
84, 70 |
40 ± 3 |
46 ± 3 |
35, 36 |
24 ± 1 |
34 ± 2* |
21, 34 |
18, 6 |
22 ± 1* |
10 |
| Cardiac index [l/min/m2] |
5.06 ± 0.30 |
5.13 ± 0.37 |
4.01, 4.5 |
5.15 ± 0.58 |
5.66 ± 0.50 |
5.65, 6.1 |
3.96 ± 0.17 |
5.36 ± 0.38* |
5.37, 5.71 |
3.58, 2.51 |
4.94 ± 0.33* |
- |
| ELWI [ml/kg] |
8±1 |
7±1 |
6, 7 |
9±0 |
8±1 |
8, 7 |
9±1 |
7±1 |
7, 7 |
8, 13 |
8±1 |
- |
| GEDI [ml/m2] |
598±28 |
620±31 |
578, 609 |
571±53 |
619±44 |
602, 579 |
524±58 |
626±28 |
653, 638 |
489, 476 |
622±41 |
- |
| SVRI [dyn.s.m2.cm-5] |
1291±45 |
1361±200 |
1080, 1307 |
887±66 |
874±85 |
670, 660 |
815±69 |
741±71 |
539, 576 |
570, 762 |
607±49 |
- |
| Mean Arterial Pressure [mmHg] |
96±9 |
99±4 |
93, 79 |
49±3 |
56±3 |
47, 46 |
38±2 |
48±1* |
36, 48 |
29, 22 |
36±1* |
34 |
| Intracranial Pressure [mmHg] |
9.3±0.8 |
9.1±0.9 |
8.2, 9.1 |
9.1±0.8 |
10.4±1.1 |
12.3, 10.4 |
13.6±1.9 |
13.9±2.3 |
14.7, 13.7 |
11.4, 16.4 |
13.9±0.8 |
24.4 |
| Intracranial temperature [°C] | 36.8±0.3 | 37.0±0.2 | 38, 37.9 | 36.9±0.2 | 37.4±0.3 | 37.6, 37.7 | 37.2±0.2 | 36.9±0.1 | 37.6, 37,3 | 36.5, 36.6 | 36.9±0.2 | 36.0 |
ELWI: extravascular lung water index. GEDI: global enddiastolic volume index. SVRI: systemic vascular resistance index.*p<0.05 (difference between Hepa Wash and control).