Table 3. Genotype and allele frequencies for the five studied polymorphisms in SORCS1 gene in Alzheimer’s patients and controls stratified by ApoE carrier status.

SNP ID		Group	n	Genotype frequency (%)			P-value	MAF	P-value
				CC	CT	TT		T
	ApoEε4(−)	AD	130	94(72.3)	34(26.2)	2(1.5)	0.899	0.15	0.94
rs17277986		control	189	136(72)	50(26.4)	3(1.6)		0.15
	ApoEε4(+)	AD	106	79(74.5)	26(24.5)	1(1)	0.675	0.13	0.72
		control	44	31(70.5)	13(29.5)	0(0)		0.15
				CC	CT	TT		T
	ApoEε4(−)	AD	130	94(72.3)	34(36.2)	2(1.5)	0.988	0.15	0.91
rs6584777		control	189	138(73)	48(25.4)	3(1.6))		0.14
	ApoEε4(+)	AD	106	79(74.5)	26(24.5)	1(1)	0.675	0.13	0.72
		control	44	31(70.5)	13(29.5)	0(0)		0.15
				GG	GA	AA		A
	ApoEε4(−)	AD	130	57(43.9)	58(44.6)	15(11.5)	0.008	0.34	0.003
rs10884402		control	189	65(34.4)	76(40.2)	48(25.4)		0.46
	ApoEε4(+)	AD	106	45(42.5)	54(50.9)	7(6.6)	0.199	0.32	0.2
		control	44	16(36.4)	21(47.7)	7(15.9)		0.4
				TT	TC	CC		C
	ApoEε4(−)	AD	130	68(52.3)	50(38.5)	12(9.2)	0.515	0.28	0.24
rs7078098		control	189	87(46)	80(42.3)	22(11.7)		0.33
	ApoEε4(+)	AD	106	49(46.2)	51(48.1)	6(5.7)	0.462	0.3	0.58
		control	44	20(45.4)	19(43.2)	5(11.4)		0.33
				CC	CT	TT		T
	ApoEε4(−)	AD	130	47(36.2)	68(52.3)	15(11.5)	0.202	0.38	0.76
rs950809		control	189	80(42.3)	80(42.3)	29(15.4)		0.37
	ApoEε4(+)	AD	106	40(37.7)	58(54.7)	8(7.6)	0.29	0.35	0.61
		control	44	21(47.7)	18(40.9)	5(11.4)		0.32

Abbreviations: MAF, minor allele frequency.

Genotypes and alleles are expressed as number (percentage). P values were calculated by χ² test 3×2 contingency table for genotype distribution and 2×2 contingency table for allele distribution.