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. 2013 May 20;8(5):e63621. doi: 10.1371/journal.pone.0063621

Table 5. Genotype and allele frequencies for rs17277986, rs6584777 stratified by gender in overall samples, Alzheimer’s patients and controls.

SNP ID Group n Genotype frequency (%) P-value MAF P-value
CC CT TT T <0.0001
rs17277986 male 256 202(78.9) 52(20.3) 2(0.8) 0.003 0.09
female 213 138(64.8) 71(33.3) 4(1.9) 0.19
CC CT TT T <0.0001
rs6584777 male 256 203(79.3) 51(19.9) 2(0.8) 0.003 0.09
female 213 139(65.2) 70(32.9) 4(1.9) 0.18
CC CT TT T 0.79
rs17277986 AD(Female) 116 75(64.6) 40(34.5) 1(0.9) 0.472 0.18
Control(Female) 97 63(64.9) 31(32) 3(3.1) 0.19
CC CT TT T 0.9
rs6584777 AD(Female) 116 75(64.6) 40(34.5) 1(0.9) 0.446 0.18
Control(Female) 97 64(66) 30(30.9) 3(3.1) 0.19
CC CT TT T 0.523
rs17277986 AD(Male) 120 98(81.7) 20(16.7) 2(1.6) 0.138 0.1
Control(Male) 136 104(76.5) 32(23.5) 0(0) 0.12
CC CT TT T 0.61
rs6584777 AD(Male) 120 98(81.7) 20(16.7) 2(1.6) 0.163 0.1
Control(Male) 136 105(77.2) 31(22.8) 0(0) 0.11

Abbreviations: MAF, minor allele frequency.

Genotypes and alleles are expressed as number (percentage). P values were calculated by χ2 test 3×2 contingency table for genotype distribution and 2×2 contingency table for allele distribution.