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L-HES-associated CD3-CD4+ T-cells do not express IL-5Rα. CD3-CD4+ T-cells from patient L-HES1 stain negatively for CD125w (grey histogram), similar to normal CD4 T-cells (white histogram) (1a), whereas basophils stain positively for this receptor (grey histogram, 1b), as expected. Identical results were obtained for CD3-CD4+ T-cells from patient L-HES2 and a third patient with L-HES.
