Table 1.
Plasma concentrations in study (starved, refed) and control mice (freely fed) from wild type and liver IGF-I knockout mice
| Freely fed | Starved | Refed | Within groups p< | Among groups p< | ||
|---|---|---|---|---|---|---|
| Glucose (mmol/l) |
wt |
10.4 ± 0.5 |
8.0 ± 0.6 |
11.3 ± 0.4 |
0.05 |
|
| |
IGF- |
12.3 ± 1.2 |
8.1 ± 0.6 |
10.0 ± 0.8 |
0.05 |
ns |
| Insulin (μg/l) |
wt |
0.58±0.09 |
0.35±0.05 |
0.93±0.16 |
0.01 |
|
| |
IGF- |
1.11±0.26 |
0.43±0.07 |
0.98±0.20 |
0.05 |
ns |
| IGF-I (μg/l) |
wt |
172 ± 13 |
138 ± 13 |
159 ± 8 |
ns |
|
| |
IGF- |
58 ± 7 |
40 ± 7 |
46 ± 7 |
ns |
0.01 |
| GH (μg/l)a |
wt |
2.0±0.8 |
5.1±2.1 |
12.6±7.3 |
ns |
|
| IGF- | 11.5±8.5 | 15±6.1 | 17.6±11.3 | ns | ns |
Mean±SEM.
A measured at 9 a.m.