Table 3. List of interactions that stabilize the gonadotropin-receptor complexes.
| hFSHR Second* - First shell | Interaction | hFSHR First shell – hFSH∞ | Interaction |
| 52R - 50E | Electrostatic | 50E - 97R | Electrostatic |
| 54V - 55L | Hydrophobic | 55L - 103Y | Hydrophobic |
| 103E - 101R | Salt bridge | 101R - 96V | Hydrophobic |
| 103E - 104K | Electrostatic | 104K - 95T | Hydrogen bond |
| - | - | 179K - 89S | Hydrogen bond |
| - | - | 179K - 90D | Salt bridge |
| 222I - 221V | Hydrophobic | 221V - 42P | Hydrophobic |
| hLHR Second*- First shell | Interaction | hLHR First shell – hLH∞ | Interaction |
| 54A - 55L | Hydrophobic | 55L - 105D | Hydrogen bond |
| - | - | 101L - 97P | Hydrophobic |
| 128C - 103Q | Hydrogen bond | 103Q - 98K | Hydrogen bond |
| - | - | 178Y - 89R | Cation-π |
| - | - | 199E - 89R | Electrostatic |
*
The second shell residues of the receptors are italicised. ∞Interacting gonadotropin residues are represented in bold.