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. 2013 May 20;8(5):e64200. doi: 10.1371/journal.pone.0064200

Figure 8. Cytokine mRNA expression in spinal cords of mice with EAE, with or without HSV vector treatment.

Figure 8

The expression patterns of LIF, STAT3, IL-5, IL-10, IL-17, IL-23, IL-6, TGF-β, IFN-γ, IFN-β and IFN-α6 mRNA expression in spinal cords are shown normalized to the housekeeping genes GAPDH and β-actin. The black bar indicates EAE without treatment, the grey bar UV-irradiated vector treatment, the orange bar treatment with HSV-Zeo and the red bar treatment with HSV-LIF. * and ** indicate significant changes (p<0.05 and p<0.01 respectively) in comparison to untreated mice at different time points. Five mice per group were included at each time point. The relative copy number values are shown on a logarithmic scale. SDs are shown.