. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Psychoneuroendocrinology. 2013 Feb 11;38(9):1553–1564. doi: 10.1016/j.psyneuen.2013.01.004

Table 4.

Impact of LFD or HFD feeding on gene expression in cerebral hippocampus, hypothalamus and cortex after 1 or 3 weeks of feeding.

		1 week		3 weeks

	Gene	LFD	HFD	LFD	HFD

	MAO-A	1.000 ± 0.033	1.078 ± 0.218	0.876 ± 0.018	1.134 ± 0.064
Hippocampus	MAO-B^#	1.000 ± 0.036^a	1.187 ± 0.195^a	0.946 ± 0.026^a	1.304 ± 0.142^b
	COMT	1.000 ± 0.050	1.055 ± 0.169	1.070 ± 0.037	1.405 ± 0.153

	MAO-A^*^#⁺	1.000 ±0.068^a	1.036 ± 0.108^a	1.624 ± 0.232^b	0.977± 0.053^a
Hypothalamus	MAO-B^*	1.000 ± 0.050^a	1.058 ± 0.138^a,b	1.855 ± 0.324^b	1.329 ± 0.174^a,b
	COMT^*⁺	1.000 ± 0.050^a	1.107 ± 0.144^a	1.869 ± 0.326^b	1.255 ± 0.103^a

	MAO-A	1.000 ± 0.132	0.890 ± 0.028	1.166 ± 0.078	0.558 ± 0.495
Cortex	MAO-B^*	1.000 ± 0.074^a	1.017± 0.031^a,b	1.315 ± 0.104^b	1.137 ± 0.136^a,b
	COMT^*	1.000 ± 0.157^a	0.753 ± 0.089^a	1.271 ± 0.108^a	1.095 ± 0.120^b

Results are expressed as relative fold change in mRNA expression (mRNA), means ± SEM.; n = 8. Results within individual rows without a common superscript letter are significantly different.

P < 0.05, significant main effect of time.

P < 0.05, significant main effect of diet.

⁺

P < 0.05, significant time-diet interaction.