Table 1.

Clinical patient characteristics prior to surgery

	n (%)	Median	Range
Age (years)		43.6	23.9–62.3
Men	18 (60)
Time between diagnosis and surgery (years)		0.4	0–4.5
Preoperative basal GH (mU/L)		27	7.6–762.0
Preoperative IGF-I (%ULN)		316	184–539
Tumor size > 10 mm	27 (90)
Received prior GH-lowering medication	11 (37)
Hypopituitarism (≥1 axis)	9 (30)
Hypogonadism	7 (23)
Hypocortisolism	5 (17)
Hypothyroidism	4 (13)
Diabetes insipidus	0 (0)
Symptoms at presentation
Acral enlargement	22 (76)
Snoring	13 (45)
Macroglossia	13 (45)
Headache	12 (41)
Increased perspiration	10 (35)
Facial changes	9 (31)
Visual field defect	7 (23)
Other visual disturbance	4 (13)

ULN upper limit of normal range