FIGURE 1.

Examples of burst firing in cerebellar granule cells. (A–C) Example of high-frequency GrC burst in the awake behaving rabbit. (A) (top) Extracellular recording of granule cell in the flocculus of a Dutch-belted rabbit during vestibular stimulation around the vertical axis. Note absence of activity prior to movement onset, whereas several distinct, high-frequency bursts occur during rotation (table position is displayed at bottom). (B)Burst demarked in A shown at larger scale. Identified spikes are indicated by dots. (C) Instantaneous frequency plot of burst shown in B. This particular burst consisted of 24 consecutive spikes with instantaneous frequencies as high as 694 Hz and had an average firing frequency of 589 Hz. (D–F) Example of high-frequency GrC burst in the awake behaving mouse. (D) (top) Extracellular recording of granule cell in crus I of an awake mouse following whisker stimulation. Note absence of activity prior to movement onset, whereas a distinct, high-frequency burst occurs during stimulation. (E)Burst demarked in D shown at larger scale. Identified spikes are indicated by dots. (F) Instantaneous frequency plot of burst shown in E. This particular burst consisted of 21 consecutive spikes with instantaneous frequencies as high as 678 Hz and had an average firing frequency of 501 Hz.