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. 2013 Jun;27(6):2220–2232. doi: 10.1096/fj.12-225615

Figure 7.

Figure 7.

RvD2 treatment inhibits neointimal hyperplasia postangioplasty. Angioplasty and local treatment of bilateral rabbit (n=8) femoral arteries with RvD2 vs. vehicle control was performed as described, and vessels were explanted at 28 d by perfusion-fixation. A, B) Histomorphometric analysis was performed on elastin-stained sections of vehicle-treated (A) vs. RvD2-treated (10 nM, B) arteries. Scale bar = 500 μm. C) Summary of morphometric results. Neointima/media (NI/M) ratio and neointimal area were significantly reduced in RvD2-treated vessels. Results are means ± se. NS, not significant. **P <0.01; paired t test.