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. 2013 Jun;27(6):2207–2219. doi: 10.1096/fj.12-225201

Figure 2.

Figure 2.

Lack of CD73 increases weight loss and enhances inflammation following intratracheal LPS instillation. A) Relative weight loss (percentage of initial individual weight) after LPS treatment (1.875 μg LPS/g body weight) in cd73+/+ and cd73−/− mice (n=6/group). P values indicate significant differences at indicated time points between genotypes, calculated by Bonferroni posttest. B) Survival curve after high-dose LPS treatment (3.75 μg/g body weight; n=8–12). C) BALF derived from cd73−/− mice 3 d after LPS application contains higher leukocyte numbers (1.875 μg LPS/g body weight; n=6–8/group). D) Lung injury scores (1.875 μg LPS/g body weight; n=4–5/group/time point). E) Representative H&E-stained tissue sections of pulmonary tissue at d 0, 3, and 14 post-LPS application, ×20 view (1.875 μg LPS/g body weight; n=4–5/group/time point).