Figure 4.

5′-NT therapy accelerates the recovery of cd73^−/− mice after intratracheal LPS instillation (3.75 μg/g body weight). A) 5′-NT-treated cd73^−/− mice recover faster than vehicle-treated cd73^−/− mice (n=12–15/group). B) Albumin content in BALF is highest in vehicle-treated cd73^−/− mice (n=5/group). C) BALF derived from vehicle-treated cd73^−/− mice contains significantly more leukocytes compared with cd73^+/+ mice, whereas cell counts from 5′-NT-treated cd73^−/− mice show intermediate numbers (n=5/group).