Table 2.

Association of IL-10 genotypes with tumor HPV16 status among patients with SCCOP

IL-10 genotype	HPV16+ patients, N = 230		HPV16− patients, N = 79		P	Adjusted OR and 95% CI
	n	%	n	%
IL-10 rs1800871					0.001
CCa	113	49.1	56	70.9		1.0
CT + TT	117	50.9	23	29.1		2.6 (1.5–4.5)
IL-10 rs1800872					0.001
CCa	109	47.4	54	68.4		1.0
CA + AA	121	52.6	25	31.7		2.4 (1.4–4.2)
IL-10 rs1800896					0.483
AAa	83	36.1	32	40.5		1.0
GA + GG	147	63.9	47	59.5		1.0 (0.6–1.8)

P values for χ² test for genotype distribution. OR and 95% CI were adjusted for age, sex, ethnicity, and tobacco smoking and alcohol consumption status in a logistic regression model.

^aReference group.