Table 4.
Correlation of IL-10 expression levels in serum with tumor HPV16 status and different genotypes of IL-10 genetic variants in 180 patients with SCCOP
| Variable | Patients (n) | Serum IL-10 level (pg/ml) | P |
|---|---|---|---|
| Tumor HPV16 status | 0.049 | ||
| Negative | 46 | 9.1 ± 8.3 | |
| Positive | 134 | 13.1 ± 12.8 | |
| IL-10 rs1800871 | 0.038 | ||
| CC | 99 | 9.6 ± 8.9 | |
| CT + TT | 81 | 12.8 ± 11.6 | |
| IL-10 rs1800872 | 0.037 | ||
| CC | 96 | 10.1 ± 8.6 | |
| CA + AA | 84 | 13.2 ± 11.1 | |
| IL-10 rs1800896 | 0.262 | ||
| AA | 68 | 10.7 ± 9.5 | |
| GA + GG | 112 | 12.6 ± 11.8 |
Serum level values are means ± sd. P values are by unpaired t test.