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The upper panel shows pre-treatment perfusion MRI studies and the lower panel shows the perfusion MRI studies after one cycle of bevacizumab for a left frontal lobe glioblastoma patient. There are increased ratios of transfer coefficient (Ktrans) (A), fractional blood volume (fBV) (B) and relative cerebral blood volume (rCBV) (C) before treatment; Ktrans (D), fBV (E) and rCBV (F) normalized after the first cycle of bevacizumab.
