Table 3.

Bolus wash-in slopes, ratios of Ktrans, fBV, and rCBV before and after one cycle of bevacizumab (n= 10 patients).

Perfusion MRI parameter	Baseline	After 1 cycle of bevacizumab	P
Bolus wash-in slopes	1.79±1.82	0.58±0.37	0.02
Ktrans*	1.79±0.78	1.24±0.21	0.03
fBV†	1.83±0.80	1.34±0.68	0.01
rCBV††	1.93±0.93	1.23±0.28	0.02

All measurements are shown as mean ± standard deviation.

^*Ktrans=transfer coefficient, a marker of microvascular permeability;

^†fBV=fractional blood volume;

^††rCBV=relative cerebral blood volume.