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. Author manuscript; available in PMC: 2013 May 21.
Published in final edited form as: Semin Immunopathol. 2010 Jul 9;32(3):239–255. doi: 10.1007/s00281-010-0214-z

Figure 3. Close association of the DZ with T zone border.

Figure 3

B cells at the base of the DZ have the potential to have intimate contact with T and DC cells near the T zone. The base of the DZ is typically long and flattened against the T cell zone. T cells and DCs (CD11c+) are present at the periphery of the DZ of mature GCs. Murine LNs were obtained 9 or 12 days after footpad immunization. Mouse immunization details are as described in Figure 1. Staining for anti-IgD-AL488 (green), anti-TCRb-bi/SA-AL568 (red) and anti-CD11c-AL647 (blue).