Table 1.
Summary of the pharmacological activities of ginseng-containing prescriptions described in the Shang-Han Lun in either animal or human studies
| Name of formula (in Korean) | Name of formula (in Chinese) | Name of formula (in Japanese) | Species | Pharmacological evaluation | References |
|---|---|---|---|---|---|
|
| |||||
| Banhasasim-tang 半夏瀉心湯 | Ban-Xia-Xie-Xin-Tang | Hangeshashin-to | Human | Dyspepsia | [3] |
| Human | Diarrhea | [4,5] | |||
| Mice | Diarrhea | [6] | |||
| Sosiho-tang 小柴胡湯 | Xiao-Chai-hu-Tang | Shosaiko-to | Rat | Anaphylaxis | [7] |
| Human | Hepatic injury | [8-14] | |||
| Rat | Hepatic injury | [15-21] | |||
| Mouse | Hepatic injury | [22] | |||
| Rat | Immune modulation | [23] | |||
| Mouse | Immune modulation | [24-32] | |||
| Insam-tang 人蔘湯 | Ren-Shen-Tang | Ninjin-to | Mouse | Diabetes | [33] |
| Guibi-tang 歸脾湯 | Gu-Pi-Tang | Kihi-to | Rat | Dementia | [34] |
| Mouse | Dementia | [35] | |||
| Rat | Osteopenia | [36] | |||
| Rat | Thrombocytopenic purpura | [37,38] | |||
| Sipjeondaebo-tang 十全大補湯 | Shi-Quan-Da-Bu- Tang | Juzentaiho-to | Mouse | Dementia | [39] |
| Human | Atopic dermatitis | [40] | |||
| Human | Anemia | [41,42] | |||
| Human | Otitis | [43] | |||
| Mouse | Cancer | [44-46] | |||
| Rat | Cancer | [47] | |||
| Mouse | Immune modulation | [48-54] | |||
| Bojungikki-tang 補中益氣湯 | Bu-Zhong-Yi-Qi -Tang | Hochuekki-to | Human | Fatigue | [55,56] |
| Mouse | Fatigue | [57,58] | |||
| Rat | Diabetes | [59] | |||
| Human | Immune modulation | [60-64] | |||
| Mouse | Immune modulation | [65-73] | |||
| Hamster | Cancer | [74] | |||
| Mouse | Lung injury | [75] | |||
| Human | Inflammation | [76,77] | |||
| Mouse | Inflammation | [78] | |||
| Rat | Osteopenia | [79] | |||
| Human | Atopic dermatitis | [80] | |||
| Rat | Liver injury | [81] | |||
| Mouse | Antibacterial | [82] | |||
| Insamyangyoung-tang 人蔘養營湯 | Ren-Shen-Yang- Rong-Tang | Ninjinyouei-to | Mouse | Anemia | [83] |
| Rat | Liver injury | [81] | |||
| Mouse | Amnesia | [84] | |||
| Mouse | Immune modulation | [85-88] | |||
| Rat | Immune modulation | [89] | |||
| Daegeonjung-tang 大建中湯 | Da-Jian-Zhong-Tang | Daikenchu-to | Mouse | Colitis | [90] |
| Rat | Liver injury | [91] | |||
| Dog | Gastrointestinal motility | [92,93] | |||
| Rat | Gastrointestinal motility | [94-96] | |||
| Mouse | Gastrointestinal motility | [97,98] | |||
| Human | Gastrointestinal motility | [99,100] | |||
| Guinea pig | Blood flow | [101,102] | |||
| Human | Blood flow | [103] | |||
| Rat | Blood flow | [104] | |||
| Saengmaek-san 生脈散 | Sheng-Mai-San | Rat | Diabetes | [105] | |
| Mouse | Amnesia | [106] | |||
| Rat | Spinal cord injury | [107] | |||
| Rat | Liver injury | [108] | |||
| Rat | Cerebral ischemia | [109-113] | |||
| Siho-ga-yonggolmoryeu-tang 柴胡加⿓骨牡蠣湯 | Chai-Hu-Jia-Long- Gu-Muli-Tang | Saikokaryukotsuborei-to | Rabbit | Atherosclerosis | [114] |
| Sihokyeji-tang 柴胡桂枝湯 | Chai-Hu-Gui-Zhi -Tang | Saikokeishi-to | Rat | Gastric ulcer | [115] |
| Rat | Liver injury | [116,117] | |||
| Mouse | Hepatic drug-metabolizing enzyme activity | [118] | |||
| Rat | Pancreatitis | [119-122] | |||
| Bekho-ga-Insam -tang 白虎加人蔘湯 | Bai-Hu-Jia-Ren- Shen-Tang | Byakkokaninjin-to | Rat | Water balance | [123] |
| Mouse | Water balance | [124] | |||
| Rat | Salivary secretion | [125] | |||
| Mouse | Salivary secretion | [126] | |||
| Mouse | Atopic dermatitis | [127,128] | |||
| Mouse | Antihyperglycaemia | [129] | |||
| Ome-whan 烏梅丸 | Wu-Mei-Wan | Ubai-gan | Rat | Colitis | [130,131] |