Fig. 2. Effects of diabetic conditions and ginseng total saponin (GTS) on the p130Cas protein assayed by Western blotting. (A) The major band for p130Cas protein at 130 kDa decreased in A30 conditions at 24 and 48 h and in B30 at 48 h incubations, which improved by GTS (1 μg/mL). Notably, GTS upregulates p130Cas of podocytes over control level even in B5. (B) Results on B5 and A30 were compared according to exposure times. Data on the densitometric analysis of p130Cas/β-tubulin (not shown) ratio are expressed as mean±SD (n=3). Control (100%), the value of B5 without GTS at each incubation time. *p<0.05, **p<0.01 vs. control.