Table 3.
Effects on glucose metabolism after cerebral IR in different days (mean ± SEM, ratio of lesion to cerebellum).
| Groups | n | Glucose metabolism of rat brain using 18F-FDG microPET | ||||
|---|---|---|---|---|---|---|
| Day 0 | Day 7 | Day 14 | Day 21 | Day 28 | ||
| Sham | 6 | 0.96 ± 0.02 | 0.91 ± 0.03 | 0.85 ± 0.03 | 0.99 ± 0.03 | 1.08 ± 0.03 |
| CIRU | 6 | 0.76* ± 0.03 | 0.67* ± 0.03 | 0.65* ± 0.03 | 0.60* ± 0.04 | 0.62* ± 0.04 |
| Scu-50 | 6 | 0.75∗w ± 0.02 | 0.71∗w ± 0.04 | 0.74** ± 0.01 | 0.75** ± 0.04 | 0.76** ± 0.03 |
| Scu-25 | 6 | 0.54* ± 0.03 | 0.49* ± 0.05 | 0.45* ± 0.02 | 0.46* ± 0.04 | 0.41* ± 0.04 |
| Nimodipine | 6 | 0.63* ± 0.03 | 0.44* ± 0.03 | 0.43* ± 0.05 | 0.40* ± 0.03 | 0.51* ± 0.02 |
Values are mean ± SD.
*P < 0.01; significantly higher compared with values of sham group.
**P < 0.01; significantly higher compared with values of CIRU group.
w P > 0.05; compared with values of CIRU group.