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. 2012 Apr 10;1(4):289–297. doi: 10.5966/sctm.2011-0016

Figure 3.

Figure 3.

Effect of TZM on in vitro angiogenesis. (A): The size and complexity of the microvascular network on Matrigel matrix after 17 days in culture differed significantly between control and TZM-treated hCDCs. (B): Continued incubation with TZM-containing medium slowed the growth and reduced the complexity of the microvascular network by >50% (n = 8 different human CDCs, each plated and analyzed in triplicate for control and TZM groups). Abbreviations: a.u., arbitrary units; hCDC, human cardiosphere-derived cells; TZM, trastuzumab.