Figure 5.
Effects of BMI on human perivascular stem cell (hPSC) yield, viability, and frequency. Samples were derived from nonoverweight (BMI <25 kg/m2), overweight (BMI 25–30 kg/m2), and obese (BMI >30 kg/m2) patients. Characteristics of cell yield, viability, and frequency were stratified by patient BMI. (A): Total SVF cell yield. (B): Percentage of DAPI− cells. (C): Percentage of CD45+ hematopoietic cells. (D): Percentage of pericytes (CD146+, CD34− cells). (E): Percentage of adventitial cells (CD146−, CD34+ cells). (F): Percentage of hPSCs (pericytes + adventitial cells). Abbreviations: BMI, body mass index; PSC, perivascular stem cell; SVF, stromal vascular fraction.