Table 2.
Associations between maternal characteristics and serum hormone concentrations among white and black mothers in first and third trimesters
| Maternal characteristics§ (per SD) |
White Mothers |
Black Mothers |
Whites vs. Blacks |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1st Trimester |
3rd Trimester |
1st Trimester |
3rd Trimester |
1st Trim |
3rd Trim |
|||||
| MC§ | p-value¶ | MC§ | p-value¶ | MC§ | p-value¶ | MC* | p-value¶ | p-value¶ | p-value¶ | |
| Testosterone (ng/ml) | ||||||||||
| Pre-pregnancy weight | 0.13 | <0.01 | 0.12 | 0.02 | 0.12 | 0.30 | 0.04 | 0.82 | 0.91 | 0.93 |
| Height | −0.12 | <0.01 | −0.17 | <0.01 | −0.11 | 0.33 | 0.14 | 0.46 | 0.91 | 0.19 |
| BMI | 0.13 | <0.01 | 0.13 | <0.01 | 0.12 | 0.25 | 0.03 | 0.88 | 0.99 | 0.45 |
| Age | −0.06 | 0.13 | −0.13 | 0.02 | −0.04 | 0.72 | −0.11 | 0.58 | 0.73 | 0.89 |
| Smoking | −0.004 | −0.89 | 0.02 | 0.61 | −0.07 | 0.53 | 0.004 | 0.98 | 0.56 | 0.87 |
| Estradiol (ng/ml) | ||||||||||
| Pre-pregnancy weight | 0.36 | 0.12 | 0.87 | 0.24 | 0.01 | 0.97 | −1.04 | 0.22 | 0.21 | 0.23 |
| Height | −0.27 | 0.27 | −1.66 | 0.03 | −0.26 | 0.19 | −0.02 | 0.98 | 0.69 | 0.33 |
| BMI | 0.34 | 0.11 | 1.00 | 0.14 | 0.04 | 0.82 | −0.80 | 0.32 | 0.29 | 0.09 |
| Age | −0.16 | 0.51 | −0.38 | 0.63 | 0.08 | 0.70 | 0.18 | 0.84 | 0.54 | 0.62 |
| Smoking | −0.06 | 0.75 | −0.19 | 0.77 | −0.22 | 0.29 | 0.10 | 0.91 | 0.59 | 0.84 |
| Estriol (ng/ml) | ||||||||||
| Pre-pregnancy weight | 0.12 | 0.51 | 0.42 | 0.32 | −0.04 | 0.69 | −1.43 | 0.01 | 0.50 | <0.01 |
| Height | −0.15 | 0.43 | −0.29 | 0.50 | −0.06 | 0.56 | 0.27 | 0.63 | 0.87 | 0.87 |
| BMI | 0.12 | 0.46 | 0.42 | 0.28 | −0.03 | 0.71 | −1.26 | 0.02 | 0.41 | <0.01 |
| Age | −0.11 | 0.55 | 0.61 | 0.17 | 0.02 | 0.86 | −0.17 | 0.78 | 0.61 | 0.17 |
| Smoking | −0.04 | 0.78 | −0.26 | 0.48 | −0.11 | 0.29 | −0.13 | 0.83 | 0.71 | 0.88 |
| Estradiol/testosterone | ||||||||||
| Pre-pregnancy weight | 0.15 | 0.46 | −0.53 | 0.41 | −0.07 | 0.63 | −0.04 | 0.94 | 0.27 | 0.89 |
| Height | 0.01 | 0.97 | 0.94 | 0.16 | −0.04 | 0.78 | −0.57 | 0.29 | 0.62 | 0.11 |
| BMI | 0.12 | 0.51 | −0.60 | 0.32 | −0.06 | 0.69 | −0.10 | 0.85 | 0.38 | 0.46 |
| Age | 0.07 | 0.74 | 1.79 | 0.01 | 0.15 | 0.34 | 0.44 | 0.43 | 0.59 | 0.16 |
| Smoking | −0.06 | 0.74 | −0.13 | 0.82 | −0.07 | 0.66 | −0.14 | 0.80 | 0.91 | 0.94 |
| Estriol/testosterone | ||||||||||
| Pre-pregnancy weight | 0.06 | 0.71 | −0.41 | 0.37 | −0.05 | 0.59 | −0.31 | 0.49 | 0.57 | 0.33 |
| Height | −0.06 | 0.73 | 1.28 | <0.01 | 0.001 | 0.99 | −0.35 | 0.45 | 0.87 | 0.02 |
| BMI | 0.06 | 0.68 | −0.56 | 0.19 | −0.04 | 0.59 | −0.22 | 0.61 | 0.49 | 0.80 |
| Age | −0.01 | 0.96 | 2.45 | <0.01 | 0.05 | 0.55 | 0.22 | 0.64 | 0.59 | <0.01 |
| Smoking | −0.02 | 0.91 | −0.27 | 0.50 | −0.05 | 0.55 | −0.22 | 0.65 | 0.76 | 0.85 |
Each maternal characteristic was rescaled by dividing its standard deviation which was calculated from the entire population
Mean change per standard deviation of each maternal characteristics.
Adjusted for gestational age of blood draw, maternal social economic index, and other maternal characteristics listed in this table.