Table 2. Correlation† of lipoprotein-associated phospholipase A2 (Lp-PLA2) level with coronary risk factor and nuclear magnetic resonance (NMR) lipoprotein subclasses among American and Japanese men.
| Americans (n=100) |
Japanese (n=93) |
|
| Age (year) | 0.02 | -0.13 |
| Waist girth (cm) | -0.20 | -0.16 |
| Body mass index (kg/m2) | -0.15* | -0.12 |
| Systolic blood pressure (mmHg) | 0.01 | -0.08 |
| Diastolic blood pressure (mmHg) | 0.01 | -0.12 |
| Total cholesterol (mg/dL) | 0.37*** | 0.30** |
| Triglycerides (mg/dL) b | 0.06 | -0.07 |
| HDL cholesterol (mg/dL) | -0.09 | 0.07 |
| LDL cholesterol (mg/dL) | 0.44*** | 0.30** |
| Fasting glucose (mg/dL) | 0.02 | -0.20* |
| Fasting insulin (μ IU/mL) | -0.11 | -0.09 |
| C-reactive protein (mg/L) b | 0.11 | 0.04 |
| Total VLDL particles (nmol/L) | 0.27** | 0.02 |
| Large VLDL/chylomicrons (nmol/L) | 0.01 | -0.07 |
| Medium VLDL (nmol/L) | 0.16 | -0.07 |
| Small VLDL (nmol/L) | 0.32** | 0.17 |
| Total LDL particles (nmol/L) | 0.14 | 0.08 |
| IDL (nmol/L) | -0.07 | -0.01 |
| Large LDL (nmol/L) | 0.52** | 0.22* |
| Small LDL (total) (nmol/L) | -0.17 | -0.05 |
| Medium small LDL (nmol/L) | -0.21* | -0.06 |
| Very small LDL (nmol/L) | -0.16 | -0.05 |
| Total HDL particles (nmol/L) | -0.10 | -0.01 |
| Large HDL (nmol/L) | 0.11 | 0.11 |
| Medium HDL (nmol/L) | -0.25* | -0.12 |
| Small HDL (nmol/L) | -0.10 | -0.06 |
| VLDL size (nm) | -0.12 | -0.15 |
| LDL size (nm) | 0.35** | 0.10 |
| HDL size (nm) | 0.12 | 0.18 |
†: Pearson's rho with normal data or Spearman's rho with skewed data.
*: <0.05, **: <0.01, ***: <0.001
LDL: low density lipoprotein
HDL: high density lipoprotein
IDL: intermediate density lipoprotein
VLDL: very low density lipoprotein