Figure 3.

A: Pair-correlation analysis quantifies the probability of finding a second protein at a certain distance r (represented by r1, r2 and r3) away from a given protein (central red circle) compared to random distribution. B: A single protein is represented by a cluster of peaks distributed over a 2D-surface representing the PSF of localization uncertainty of the PALM experiment. Autocorrelation function of the protein at r=0, g(r)^centroid, is a delta function represented by red spike at the centroid of the protein. g(r)^centroid is convolved with the autocorrelation function of the PSF. The resulting Gaussian function, g(r)^stoch, quantifies the spatial distribution of multiple peaks arising from a single molecule.