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. Author manuscript; available in PMC: 2013 May 21.
Published in final edited form as: J Cell Physiol. 2012 May;227(5):1883–1890. doi: 10.1002/jcp.22916

Figure 6. Afadin depletion attenuates OxPAPC-mediated adherens junction and tight junction remodeling.

Figure 6

Pulmonary EC were transfected with: A - non-specific RNA, or B - afadin-specific siRNA. Cells were stimulated with OxPAPC (10 μg/ml, 30 min) followed by double immunofluorescence staining for ZO-1 (green) and p120-catein (red). Merged images depict areas of OxPACP-induced protein co-localization which appear in yellow and marked by arrows. This effect was attenuated in afadin-depleted EC. Shown are representative results of three independent experiments.