Figure 2.

Significantly increased (A) and decreased (B) expression (**, p<0.01) of HHIP target genes associated with extracellular matrix (ECM) after HHIP silencing in Beas-2B cells, as measured by TaqMan assay-based RT-PCR. Three different HHIP-targeted shRNAs were used for knock-down. Relative expression values were calculated as described in Materials and Methods and represent means ± standard errors from two independent shRNA infections.