Figure 4. Silencing of GHRH-R mRNA with siRNA significantly suppressed GHRH gene expression by HCC1806 but not by MX-1.

Silencing resulted in an 80% reduction in the expression of GHRH-R genes by both HCC1806 and MX-1 cells. Vertical bars indicate ± SEM, n=9 samples, * P < 0.01 vs. control, † P < 0.05 vs. control.