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. 2013 Feb 20;24(6):1574–1579. doi: 10.1093/annonc/mdt019

Table 1.

Distribution of sociodemographic and clinical characteristics among colorectal cancer patients (n = 6803) aged ≥65 diagnosed from 2005–2007 receiving chemotherapy with versus without bevacizumab (BEV) for metastatic or recurrent disease

Population characteristics Total % (N = 6803) No Bev % (N = 4016) Bev % (N = 2787)
Age at first chemotherapy (years)
 65–69 29 29 30
 70–74 27 26 27
 75–80 24 24 24
 80+ 20 20 19
Sex
 Female 50 50 49
 Male 50 50 51
Race
 White 84 83 84
 Black 8 8 8
 Other 8 9 8
AJCC stage at diagnosis**
 2 18 23 12
 3 44 54 28
 4 38 23 60
Revised comorbidity indexa
 None 60 59 61
 1 28 29 26
 2+ 12 12 13
History of medical conditionsb
 Cardiac disease**
  Yes 60 62 56
  No 40 38 44
 Arterial thromboembolic events (ATEs)*
  Yes 5 6 4
  No 95 94 96
Congestive heart failure/cardiomyopathy (CHF/CM)
 Yes 12 13 11
 No 88 87 89

aCharlson's Index with exclusion of myocardial infarction and congestive heart failure.

bHistory of general cardiac conditions includes the following diseases: hypertension, arrhythmic disorders, cardiomyopathic disorders, pericardial disorder, aortic wall disorders, and cardiopulmonary arrest.

* and ** indicated a variable with an unadjusted chi-square P value smaller than 0.001 and 0.0001, respectively.