Table 1.
Paternal age (years) | Count of cases | % | Count of controls | %t | Adjusted Odds Ratio | Lower 95% CI | Upper 95% CI |
---|---|---|---|---|---|---|---|
<20 | 297 | 1.44 | 1561 | 1.56 | 0.98 | 0.85 | 1.12 |
20–24 | 3005 | 14.60 | 16027 | 16.00 | Reference | ||
25–29 | 5436 | 26.41 | 28877 | 28.83 | 1.03 | 0.97 | 1.08 |
30–34 | 5075 | 24.66 | 25156 | 25.11 | 1.09 | 1.03 | 1.16 |
35–39 | 3517 | 17.09 | 16092 | 16.06 | 1.16 | 1.08 | 1.24 |
40–44 | 1960 | 9.52 | 8145 | 8.13 | 1.25 | 1.16 | 1.36 |
45–49 | 874 | 4.25 | 3032 | 3.03 | 1.50 | 1.35 | 1.66 |
50–54 | 281 | 1.37 | 918 | 0.92 | 1.59 | 1.37 | 1.85 |
≥ 55 | 137 | 0.67 | 368 | 0.37 | 1.95 | 1.58 | 2.40 |
Maternal age | |||||||
<20 | 1380 | 6.70 | 6952 | 6.94 | 1.06 | 0.99 | 1.14 |
20–24 | 5271 | 25.61 | 27789 | 27.74 | Reference | ||
25–29 | 5896 | 28.65 | 30520 | 30.47 | 0.98 | 0.94 | 1.03 |
30–34 | 4430 | 21.52 | 20344 | 20.31 | 1.05 | 1.00 | 1.11 |
35–39 | 2647 | 12.86 | 10917 | 10.90 | 1.10 | 1.03 | 1.17 |
40–44 | 879 | 4.27 | 3411 | 3.41 | 1.07 | 0.97 | 1.17 |
≥ 45 | 79 | 0.38 | 243 | 0.24 | 1.21 | 0.93 | 1.58 |
Adjusted for age of spouse, birth year and sex of proband
Significant results shown in bold