Table 3.
Association of the fasting NEFA levels with the risk of diabetes – adjustment for and stratification by metabolic risk factors
| Variables included in the modela | Stratification by baseline characteristics OR (95% CI) (n) |
||
|---|---|---|---|
| All | Sub-groups | ||
| Log (NEFA) (Model1) | 1.37 (0.87, 2.15) (902) |
NGT 0.83 (0.40, 1.73) (601) |
IGT 0.66 (0.34, 1.27) (301) |
| Log (NEFA), 2 hr glucose | 0.50 (0.30, 0.82) (902) |
NGT 0.57 (0.27, 1.20) (601) |
IGT 0.50 (0.25, 1.01) (301) |
| Log (NEFA), FPG | 0.97 (0.60, 1.55) (902) |
FPG < 110 0.99 (0.57, 1.75) (754) |
FPG ≥ 110 0.95 (0.37, 2.45) (148) |
| Log (NEFA), BMI | 1.08 (0.69, 1.71) (900) |
Normal (BMI <25.0) 0.62 (0.21, 1.78) (234) |
Overweight/Obese (BMI ≥25.0) 1.21 (0.72, 2.02) (666) |
| Log (NEFA), waist-to-hip ratio (WHR) | 1.22 (0.77, 1.93) (899) |
WHR < 0.857 (median) 1.21 (0.58, 2.54) (448) |
WHR ≥ 0.857 (median) 1.18 (0.65, 2.15) (451) |
| Log (NEFA), waist | 1.08 (0.68, 1.71) (899) |
Waist < 89.5 (median) 0.86 (0.41, 1.80) (449) |
Waist ≥ 89.5 (median) 1.22 (0.68, 2.22) (450) |
| Log (NEFA), weight | 1.15 (0.73, 1.81) (900) |
Weight < 77.84 (median) 0.73 (0.34, 1.57) (449) |
Weight ≥ 77.84 (median) 1.41 (0.77, 2.57) (451) |
| Log (NEFA), SI | 1.01 (0.60, 1.70) (838) |
SI < 2.65 (median) 1.01 (0.51, 1.98) (421) |
SI ≥ 2.65 (median) 0.82 (0.36, 1.87) (417) |
| Log (NEFA), fasting insulin | 1.17 (0.74, 1.85) (901) |
Fasting insulin < 13 (median) 1.10 (0.48, 2.51) (433) |
Fasting insulin ≥ 13 (median) 1.13 (0.65, 1.98) (468) |
| Log (NEFA), AIR (MM) | 1.40 (0.88, 2.23) (878) |
AIR < 374.42 (median) 1.42 (0.82, 2.47) (438) |
AIR ≥ 374.42 (median) 1.17 (0.48, 2.86) (440) |
a
All models also included the following demographic and study variables: age, ethnicity, gender, study site