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. 2013 Apr 24;9:86. doi: 10.1186/1746-6148-9-86

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Copyright © 2013 Bartel et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Alterations of proliferative activity in 3D cultured canine endometrial cells due to 17β-estradiol and progesterone supplementation. Percentage of anti-Ki67 positive glandular epithelial cells (GECs) and stromal cells (SCs) indicating proliferative activity after 24 and 48 hr of 3D cell culture with (A) 17β-estradiol (E) and (B) progesterone (P) supplementation in the respective three different concentrations. Statistical significances (p < 0.05) are indicated as letters (A-E for GECs, a-e for SCs) above the related columns.