Table 1.
Differences in the expressions of genes (normalized and log2-transformed intensities) related to pluripotency, embryonic stem cells and embryogenesis in FACS-isolated small putative ovarian stem cells (OSCs) in comparison with fibroblasts (FBs) revealed using the Student’s T test
| Log fold change | p-value | Adj. p-value | |
|---|---|---|---|
|
POU5F1 |
0.78 |
0.122520121 |
1.64E-01 |
|
SALL4 ** |
5.41 |
0.000714457 |
2.23E-03 |
|
CDH1 ** |
3.21 |
0.018838123 |
3.21E-02 |
|
LIN28B ** |
5.11 |
0.005075958 |
1.06E-02 |
|
NANOG |
0.86 |
0.552979106 |
6.08E-01 |
|
SOX2 |
−2.15 |
0.023394118 |
3.87E-02 |
|
SOX11 ** |
2.90 |
0.000290721 |
1.18E-03 |
|
DPPA3 |
−2.19 |
0.048897088 |
7.36E-02 |
|
LEFTY1 ** |
4.23 |
0.000384105 |
1.42E-03 |
|
ZIC3 ** |
3.79 |
9.29E-05 |
5.66E-04 |
|
ZIC5 |
−0.63 |
0.090116973 |
1.25E-01 |
|
PRDM14 ** |
3.63 |
0.003039563 |
6.94E-03 |
|
GAL |
1.58 |
0.26269284 |
3.19E-01 |
|
PPP1R9A ** |
1.55 |
0.006663692 |
1.33E-02 |
|
SMO |
−0.68 |
0.545353659 |
6.01E-01 |
|
MMP25 * |
−2.43 |
0.006783372 |
1.35E-02 |
|
MLLT4 |
−1.10 |
0.211498682 |
2.64E-01 |
|
BMP7 |
0.73 |
0.515756119 |
5.73E-01 |
|
MYBL2 ** |
2.35 |
0.006965786 |
1.38E-02 |
|
DNMT3B ** |
2.64 |
0.000957838 |
2.79E-03 |
|
ZFP42 |
1.05 |
0.148285014 |
1.94E-01 |
|
HESRG ** |
6.89 |
0.000200358 |
9.14E-04 |
|
ZSCAN10 |
1.37 |
0.130067706 |
1.73E-01 |
|
TRO |
−1.13 |
0.456996609 |
5.17E-01 |
| DDX11 | −2.57 | 0.015893686 | 2.78E-02 |
P-values were adjusted for the effect of multiple testing according to Benjamini-Hochberg (limma, Bioconductor, programme R 2.14.1). Statistical significance was set at p < 0.05. Legend: ** – genes up-regulated in OSCs, * – genes down-regulated in OSCs.