Table I.
Activation area | Healthy subjectsa | Bipolar disorder | ||
---|---|---|---|---|
z | x, y, z | z | x, y, z | |
Left and right medial temporal regions | ||||
Left Parahippocampal Gyrus (BA 28, 29 and 35) | 5.64 | −24, −28, −8 | 4.28 | −26, −30, −6 |
Left Hippocampus | 3.69 | −34, −18, −20 | 4.59 | −26, −32, −2 |
Left Amygdala | 3.31 | −32, −4, −16 | – | |
Right Parahippocampal Gyrus (BA 27, 28 and 35) | 6.49 | 24, −30, −6 | 5.01 | 18, −32, −6 |
Right Hippocampus | 3.18 | 26, −10, −20 | – | |
Right Amygdala | 3.03 | 24, −6, −20 | – | |
Left lateral prefrontal cortex | ||||
Middle Frontal Gyrus (BA 46) | 5.67 | −46, 28, 20 | 4.73 | −44, 18, 26 |
Middle Frontal Gyrus (BA 9) | 5.21 | −38, 4, 26 | 3.74 | −48, 14, 22 |
Middle Frontal Gyrus (BA 6 & 8) | 4.75 | −48, 4, 46 | 4.28 | −44, 2, 42 |
Inferior Frontal Gyrus (BA 47) | 4.81 | −50, 36, −2 | 4.51 | −46, 42, −2 |
Right Lateral Prefrontal Cortex | ||||
Middle Frontal Gyrus (BA 46) | 5.58 | 42, 28, 14 | 4.42 | 44, 32, 18 |
Inferior and Middle Frontal Gyrus (BA 9) | 3.62 | 42, 16, 28 | 3.94 | 46, 6, 30 |
Precentral Gyrus (BA 6) | 4.99 | 38, 6, 22 | 3.89 | 36, 6, 26 |
Left medial prefrontal cortex | ||||
Cingulate Gyrus (BA 32) | 5.36 | −8, 24, 36 | 4.09 | −6, 16, 44 |
Superior Frontal Gyrus (BA 6 & 8) | 6.01 | −6, 14, 46 | 3.85 | −8, 18, 58 |
Left and right parietal cortex | ||||
Left Precuneus (BA 19) | 5.24 | −30, −72, 36 | 3.28 | −34, −68, 38 |
Left Inferior and Superior Parietal Lobule (BA 7 and 39) | 4.29 | −28, −68, 24 | 3.51 | −36, −64, 40 |
Right Precuneus (BA 19) | 5.67 | 34, −64, 42 | – | |
Right Angular Gyrus (BA 39) | 5.46 | 32, −62, 34 | – | |
Bilateral occipital lobe and cerebellum | ||||
Middle and Inferior Occipital Gyri (BA 18) | 6.47 | 30, −86, −14 | 5.15 | −32, −96, 2 |
Lingual Gyrus (BA 17 and 18) | 6.18 | −18, −102, −16 | 5.82 | 0, −76, −4 |
Fusiform Gyrus (BA 18 and 19) | 6.03 | 26, −96, −14 | 5.33 | 22, −88, −14 |
Cerebellum (Declive, Culmen and Tuber) | 6.68 | 34, −84, −22 | 6.01 | −28, −72, −22 |
Left lateral temporal cortex | ||||
Middle Temporal Gyrus (BA 21) | – | 4.39 | −58, −36, −2 |
Value and Talairach coordinate for the maximum z‐statistic in that area for each group separately.