Table 3. Cross-platform validation of the gene signatures.

Gene signature	No. of samples	Overlapping genes	Sensitivity (TP)	Specificity (TN)	Accuracya	p-valueb
Basal BRCA1 signature	20 vs. 10	95/110	0.95 (19)	0.90 (9)	0.93	6.7×10−6
LumB BRCA2 signature	16 vs. 46	92/100	0.94 (15)	0.96 (44)	0.96	2.2×10−11

Validation of the basal BRCA1 signature and lumB BRCA2 signature were performed using samples analyzed by in-house spotted microarrays. Classification performances were assessed by leave-one-out cross-validation. TP, true positive; TN, true negative.

^aMean balanced accuracy.

^bFisher's exact test.