Table 2. Baseline vascular and laboratory values.
| Eplerenone group N = 26 | Control group N = 25 | |
| Mean (SD) | Mean (SD) | |
| Indices of arterial stiffness | ||
| cfPWV (m/s) | 10.1 (4.0) | 9.8 (3.3) |
| AIx (%) | 22.3 (11.1) | 24.6 (9.4) |
| AIx@HR75 (%) | 16.7 (10.3) | 19.2 (7.9) |
| AASI (units) | 0.47 (0.12) | 0.46 (0.14) |
| Blood pressure data | ||
| systolic office BP (mmHg) | 126 (15) | 129 (15) |
| diastolic office BP (mmHg) | 77 (8) | 79 (11) |
| central systolic BP (mmHg) | 116 (14) | 119 (15) |
| central diastolic BP (mmHg) | 78 (8) | 80 (11) |
| 24 h systolic BP (mmHg) | 126 (10) | 127 (17) |
| 24 h diastolic BP (mmHg) | 73 (8) | 75 (10) |
| Renal data | ||
| P-creatinine (mg/dL) | 1.97 (0.53) | 2.09 (0.63) |
| P-urea (mg/dL) | 37.8 (14.6) | 39.2 (15.1) |
| P-potassium (mEq/L) | 4.3 (0.4) | 4.3 (0.5) |
| P-bicarbonate (mEq/L) | 24 (3) | 25 (3) |
| eGFR (mL/min/1.73 m2) | 36 (10) | 35 (13) |
| Creatinine clearance (mL/min) | 54 (23) | 55 (26) |
| Urinary albumin (mg/24 h)* | 241 (121, 479) | 208 (89, 486) |
Note: Conversion factors for units: p-creatinine in mg/dL to µmol/L, ×88.4; p-urea in mg/dL to mmol/L, ×0.357. No conversion necessary for p-potassium or p-bicarbonate in mEq/L and mmol/L.
AASI, Ambulatory Arterial Stiffness Index; AIx, Augmentation Index; AIx@HR75, Augmentation Index adjusted for heart rate 75 beats/minute; BP, blood pressure; cfPWV, carotid-femoral pulse wave velocity; eGFR, estimated glomerular filtration rate;
Indices of arterial stiffness are a mean of two measurements per patient, except AASI.
*
24 h urinary albumin excretion is presented as geometric means with 95% CI.
All P-values>0.05.