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. 2013 May 21;8(5):e64716. doi: 10.1371/journal.pone.0064716

Figure 2.

Figure 2

Clinical outcomes in early and advanced HL according to miR-SNPs. DFS in early-stage HL patients according to KRT81 and TRBP and in advanced HL patients according to XPO5. And OS in advanced-stage HL patients according to XPO5. (A) DFS was 72.3 months (95% CI, 59–86) for patients with the KRT81 CG genotype and 114.3 months (95% CI, 103–125) for those with the TT or TC genotype (P = 0.037). (B) A trend towards an association between the TRBP genotype and DFS in early-stage patients was also observed; mean DFS was 117 months (95% CI, 105–129) for patients with the TT genotype, compared to 92 months (95% CI, 78–106) for those with the CC or TC genotype (P = 0.081). (C) All patients with the XPO5 AC genotype were disease-free at the time of this analysis, while mean DFS among patients with the AA or CC genotype was 30.9 months (95% CI, 18–44) (P = 0.002). (D) OS was 133 months (95% CI, 118–148) in patients harboring the AC genotype compared to 74 months (95% CI, 55–94) for those with the AA or CC genotype (P = 0.035).