Figure 5. AR suppression recapitulates the effect of c-Myc suppression on c-Myc target gene expression.

LNCaP and abl cells were transfected with 50 nM of non-targeted control (NTC) and either A) AR or B) c-Myc RNAi oligonucleotides. Cells were switched to charcoal-stripped serum on the day of transfection and harvested 96 hours later. QRT-PCR was performed to determine the levels of the indicated c-Myc target genes relative to actin. *denotes p<0.05 compared to NTC.