Table 1.
List of Analytes Examined.
| Amino Acids (umol/L) |
| Alanine (ALA) |
| Arginine (ARG) |
| Argininosuccinate (ASA)a |
| Citrulline (CIT) |
| Glutamate (GLU) |
| Glycine (GLY)b |
| Leucine (LEU) |
| Methionine (MET) |
| Ornithine (ORN)b |
| 5-oxoproline (5-OxoPro)b |
| Phenylalanine (PHE) |
| Tyrosine (TYR) |
| Valine (VAL) |
| Acylcarnitines (umol/L) |
| Carnitine free (C0) |
| Acetylcarnitine (C2) |
| Propionylcarnitine (C3) |
| Malonylcarnitine (C3-DC) |
| Butyrylcarnitine+Isobutyrylcarnitine (C4) |
| Methylmalonylcarnitine (C4-DC) |
| 3-Hydroxybutyrylcarnitine (C4-OH)b |
| Isovalerylcarnitine+Methylbutyrylcarnitine (C5) |
| Tiglylcarnitine (C5:1)a |
| Glutarylcarnitine (C5-DC) |
| 3-Hydroxyisovalerylcarnitine (C5-OH) |
| Hexanoylcarnitine (C6) |
| Methylglutarylcarnitine (C6-DC) |
| Octanoylcarnitine (C8) |
| Octenoylcarnitine (C8:1) |
| Suberylcarnitine (C8-DC)b |
| Decanoylcarnitine (C10) |
| Decenoylcarnitine (C10:1) |
| Decadienoylcarnitine (C10:2)b |
| Dihydrosebacylcarnitine (C10-DC)b |
| Dodecanoylcarnitine (C12) |
| Dodecenoylcarnitine (C12:1) |
| Tetradecanoylcarnitine (C14) |
| Tetradecenoylcarnitine (C14:1) |
| Tetradecadienoylcarnitine (C14:2) |
| 3-Hydroxytetradecanoylcarnitine (C14-OH)a |
| Palmitoylcarnitine (C16) |
| Palmitoleylcarnitine (C16:1) |
| 3-Hydroxypalmitoleylcarnitine (C16:1-OH)a |
| 3-Hydroxypalmitoylcarnitine (C16-OH)a |
| Stearoylcarnitine (C18) |
| Oleoylcarnitine (C18:1) |
| 3-Hydroxyoleoylcarnitine (C18:1-OH)a |
| Linoleoylcarnitine (C18:2) |
| 3-Hydroxylinoleoylcarnitine (C18:2-OH)b |
| 3-Hydroxystearoylcarnitine (C18-OH)a |
a
results are not presented for these metabolites that had low variability (standard deviation is ≤0.01umol/L)
b
metabolites added or dropped from the tandem mass spectrometry panel within collection period