Table 5.
Immunophenotypic features of the tumor and IEL in bowel distant to tumor
| Without CD (n = 4) |
With CD (n = 1) |
||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| Tumor, IHC | |||||
| βF1 | − | − | − | − | − |
| TCRδ | + | + | + | + | + |
| TCRγ | + | + | + | + | + |
| CD2 | + | − | + | − | + |
| CD3 | + | + | + | + | + |
| CD5 | − | − | − | − | − |
| CD7 | + | + | + | + | + |
| CD4 | − | − | − | − | − |
| CD8 | − | − | + | − | + |
| CD56 | + | + | + | + | − |
| TIA-1 | + | + | + | + | + |
| Granzyme B | − | − | − | + | − |
| CD30 | − | − | − | − | − |
| CD25 | − | − | − | − | − |
| PD1 | + | − | − | − | − |
| FOXP3 | − | − | − | − | − |
| CD20 | − | − | − | − | − |
| EBER | − | − | − | − | − |
| p53 | − | − | + | − | − |
| Tumor, flow cytometry | |||||
| αβ−, γδ+ | Not done | Not done | + a | Not done | + b |
| CD103+ | Not done | Not done | + | Not done | + b |
| Intraepithelial lymphocytes in bowel distant to tumor, IHC | |||||
| CD3 | + | + | + | + | + |
| CD5 | − | − | − | − | − |
| CD8 | + | + | − | − | + |
| CD56 | − | − | − | + | − |
| TIA-1 | + | + | + | + | + |
| Granzyme B | − | − | − | − | − |
a
Cells were probably γδ+, but interpretation was somewhat difficult. CD103 expression was weak.
b
Cells were apparently γδ+ and possibly CD103+, but interpretation was somewhat difficult.