Figure 2. Fluoro Jade (FJ) and Cresyl violet staining, was assessed to study neurodegeneration and cell morphology.

It was observed that Hypobaric hypoxia leads to neurodegeneration and cell pyknosis as evident from increased number of FJ positive cells and pyknotic cells whereas enriched environment decreases number when compared to hypobaric hypoxia alone group. Data represents Mean ± SEM. “*” and “**” represents p<0.001 when compared to control and hypoxic group.