Figure 3. Effect of Trk antagonist on Behavior was studied using Morris Water Maze test and representative tack sheet showing memory test of Normoxia (I), Hypoxia (II), Enriched environment + Hypoxia (III) and Enriched environment + hypoxia + K252a (IV) exposure.

Inhibition of TrkB with K252a nullifies the protective effect of Enriched environment on hypobaric hypoxia induced memory impairment as evident from increased pathlength (A) and latency (B) and decreased No. of platform crossing (C) and time spent in target quadrant (D). Data represents Mean ± SEM. “*” and “#” represents p<0.001 when compared to control and hypoxic group whereas “**” represents p<0.05 when compared to hypoxic group.