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. Author manuscript; available in PMC: 2014 May 20.
Published in final edited form as: Chem Res Toxicol. 2013 Apr 15;26(5):634–644. doi: 10.1021/tx400049s

Figure 5.

Figure 5

Tyrosinase expression (a) was induced upon PCB126 treatment and in a near dose-dependent manner whereas dietary copper had little effect. PCB126 treatment significantly decreased cytochrome c oxidase subunit I (b) and subunit IV (c) gene expression. PCB126 treatment and dietary copper increased the expression of both MT1 and MT2. Fold change is calculated relative to 6ppm dietary copper and corn oil treatment. Error bars represent SEM. Each group contained 4–6 animals. * p < 0.05 as compared to adequate (6 ppm) dietary copper. † p < 0.05 as compared to Corn Oil vehicle control.