Table 1.
Two-way ANOVA analysis of the effects of dietary copper, PCB126, and interaction
| Dietary Copper | PCB126 | Interaction Effect | |
|---|---|---|---|
| Growth Rate (%) | - | ↓<0.0001 | - |
| Feed Consumption | - | ↓<0.0001 | - |
| Rel. Liver Weight (%) | ↓0.0227 | ↑<0.0001 | - |
| Rel. Kidney Weight (%) | - | - | - |
| Liver EROD Activity | - | ↑<0.0001 | - |
| Liver MnSOD Activity | - | ↓0.0037 | - |
| Liver CuZnSOD Activity | - | - | - |
| Liver Total SOD Activity | - | - | - |
| Liver Glutathione | ↓0.0005 | ↓0.0026 | - |
| Serum Cp | ↑<0.0001 | - | 0.0019 |
| Liver 4-HNE | - | ↓0.0145 | - |
| Liver Cp Expression | ↑0.0197 | - | - |
| Liver Tyr Expression | - | ↑0.0066 | - |
| Liver CytOxI Expression | - | ↓<0.0001 | - |
| Liver CytOxIV Expression | - | ↓<0.0001 | 0.0002 |
| Liver MT1 Expression | ↑0.0001 | ↑<0.0001 | - |
| Liver MT2 Expression | ↑0.0072 | ↑<0.0001 | - |
| Liver Copper | ↑<0.0001 | ↑<0.0001 | 0.0001 |
| Liver Selenium | ↑0.0011 | ↓<0.0001 | 0.0020 |
| Liver Iron | - | ↓0.0002 | - |
| Liver Zinc | ↑<0.0001 | ↓<0.0001 | - |
| Liver Manganese | ↑0.0006 | ↓<0.0001 | - |
| Kidney Copper | ↑<0.0001 | ↑0.0005 | - |
| Kidney Selenium | ↑<0.0001 | ↑<0.0001 | - |
| Kidney Iron | - | - | - |
| Kidney Zinc | ↑0.0017 | - | - |
| Kidney Manganese | ↑0.0081 | ↑0.0111 | - |
| Blood Copper | ↑<0.0001 | ↑0.0281 | 0.0013 |
| Blood Selenium | ↑0.0026 | - | - |
| Blood Iron | ↑0.0130 | - | - |
| Blood Zinc | - | ↓0.0019 | - |
| Blood Manganese | ↓0.0001 | - | - |
Only p-values <0.05 are reported