Table 3.
CuZnSOD, MnSOD, and Total SOD activity (U/mg protein) under each experiment condition and significance of various comparisons (adjusted using Dunnett's test)
| CuZnSOD Activity (U/mg protein) | MnSOD Activity (U/mg protein) | Total SOD Activity (U/mg protein) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| Treatment | Dietary Copper Level | Dietary Copper Level | Dietary Copper Level | |||||||||
|
| ||||||||||||
| Low (2 ppm) | Adequate (6 ppm) | High (10 ppm) | Overall | Low (2 ppm) | Adequate (6 ppm) | High (10 ppm) | Overall | Low (2 ppm) | Adequate (6 ppm) | High (10 ppm) | Overall | |
| Corn Oil | 256 ± 36 (-,-) | 223 ± 25 (-,-) | 224 ± 40 (-,-) | - | 83.1 ± 3.9 (-,-) | 91.4 ± 5.5 (-,-) | 98.6 ± 9.2 (-,-) | - | 339 ± 37 (-,-) | 314 ± 27 (-,-) | 323 ± 36 (-,-) | - |
| 1 μmol/kg PCB126 | 240 ± 26 (-,-) | 270 ± 32 (-,-) | 284 ± 61 (-,-) | - | 68.6 ± 9.9 (-,-) | 74.5 ± 7.6 (-,-) | 82.6 ± 6.5 (-,-) | † | 308 ± 29 (-,-) | 344 ± 32 (-,-) | 367 ± 60 (-,-) | - |
| 5 μmol/kg PCB126 | 225 ± 27 (-,-) | 296 ± 40 (-,-) | 283 ± 33 (-,-) | - | 67.6 ± 8.3 (-,-) | 81.8 ± 8.1 (-,-) | 61.7 ± 5.5 (*,-) | † | 293 ± 26 (-,-) | 378 ± 47 (-,-) | 344 ± 32 (-,-) | - |
|
| ||||||||||||
| Overall | - | - | - | - | - | - | - | - | - | |||
Results are expressed as mean ± SEM. Each group contained 4–6 animals. One-way AN OVA was used to examine the difference between each PCB126 level and the corn oil treatment, "†" in the parentheses indicates a significant difference due to PCB treatment. Similarly, a "*" in the parentheses indicates significant differences between low or supplemental and the adequate dietary copper level. Significance for each factor based on two-way ANOVA is indicated in the bottom margin for copper diet (*) and in the right margin for PCB treatment (†). The level for significance is 0.05.