Table II.
Specific DH gene starting positions and reading frames that are over presented. The first column is the DH gene, the second column the DRF, the third column is the position in the DH gene used as a beginning of the DH gene. The last columns represent the nucleotide and amino acids of the resulting DH genes. An interesting QLV motif appears in many of the sequences. The nucleotide sequences are not the full germline sequences, but the relative regions translated, taking into account the DRF and the starting position in each case.
| DH gene | DRF | Starting position (nucleotide) | nt sequence | aa sequence |
|---|---|---|---|---|
| IGHD1–20 | 1 | 4 | ATAACTGGAACGAC | ITGT |
| IGHD1–20 | 2 | 5 | AACTGGAACGAC | NWND |
| IGHD1–26 | 3 | 6 | TGGGAGCTACTAC | WELL |
| IGHD3–22 | 1 | 18 | TGGTTATTACTAC | WLLL |
| IGHD4–17 | 1 | 2 | CTACGGTGACTAC | LR*L |
| IGHD6–13 | 2 | 8 | CAGCAGCTGGTAC | QQLV |
| IGHD6–19 | 2 | 8 | CAGTGGCTGGTAC | QWLV |
| IGHD6–25 | 2 | 8 | CAGCGGCTAC | QRL |
| IGHD6–6 | 2 | 7 | CAGCTCGTCC | QLV |
| IGHD6–6 | 2 | 8 | CAGCTCGTCC | QLV |