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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: J Neurochem. 2013 Mar 18;125(5):663–672. doi: 10.1111/jnc.12229

Fig. 2.

Fig. 2

Quinpirole stimulated DAT recycling without an effect on DAT internalization. N2A cells transiently transfected with HA-DAT and FLAG-D2S were treated with vehicle (V), quinpirole (100 nM, 30 min), LY379196 (100 nM), or LY+Q. (A) Representative blots and summary of the DAT recycling (N=6). Quinpirole accelerated the DAT recycling rate compared to the vehicle treatment (*p<0.05). LY379196 itself did not have an effect on DAT recycling, but blocked quinpirole-induced increased DAT recycling. (B) Representative blots and summary of DAT internalization (N=5). The DAT internalization rate did not differ between quinpirole and vehicle treatment and LY379196 did not affect DAT internalization either. The data from the LY+Q group did not differ from V+V or LY+V. Error bars represent SEM.