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. 2013 May 21;8(5):e63402. doi: 10.1371/journal.pone.0063402

Figure 2. The levels of heme transporters involved in heme uptake are enhanced in lung cancer cells.

Figure 2

The normal HBEC30KT lung epithelial (HBEC) and NSCLC HCC4017 (HCC) cells were cultured and treated as indicated. Protein extracts were prepared and the levels of HCP1 and HRG1 were detected by Western blotting. The protein level of β-actin in the samples was used for normalization. (A) The protein level of heme transporter HCP1 in normal and NSCLC cells. (B) The protein level of heme transporter HRG1 in normal and NSCLC cells. For statistical analysis, the levels in cancer cells were compared to the levels in normal cells, by using Welch 2-sample t-test. **, p value <0.005.