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. 2013 May 21;8(5):e63402. doi: 10.1371/journal.pone.0063402

Figure 3. The levels of oxygen utilizing hemoproteins are enhanced in lung cancer cells.

Figure 3

The normal HBEC30KT lung epithelial (HBEC) and NSCLC HCC4017 (HCC) cells were cultured and treated as indicated. Protein extracts were prepared and the levels of hemoproteins were detected by Western blotting. The protein level of β-actin was used for normalization. (A) The protein level of cytoglobin in normal and NSCLC cells. (B) The protein level of cytochrome c in normal and NSCLC cells. (C) The protein level of CYP1B1 in normal and NSCLC cells. (D) The protein level of Cox-2 in normal and NSCLC cells. For statistical analysis, the levels in cancer cells were compared to the levels in normal cells, by using Welch 2-sample t-test. *, p value <0.05; **, p value <0.005.